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2025-08-14 17:11
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In its 2016 opinion, the ANS Panel recommended new studies be carried out to fill the gaps on possible effects on the reproductive system, which could enable them to set an Acceptable Daily Intake (ADI ). Uncertainty around the characterisation of the material used as the food additive (E 171) was also highlighted, in particular with respect to particle size and particle size distribution of titanium dioxide used as E 171.
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In some studies, E171 was given to animals in drinking water without the stabilizers that keep E171 suspended in the liquid. Without stabilizers, E171 can settle and prevent the ingredient from combining with surrounding ingredients.